Predictive Parameters of Steroid Dependency in Minimal Change Disease

The most common type of nephrotic syndrome in children is minimal change disease (MCD), which usually responsive to steroid therapy. Steroid dependency one the handicaps management these children. Thus, early prediction course may improve treatment strategy. Demographic characteristics and laboratory parameters 35 patients at time MCD diagnosis were retrospectively obtained from hospital records. There 23 (65%) with sensitive (SSNS) 12 (35%) dependent (SDNS). was a significant difference between SSNS SDNS terms age diagnosis, remission time, mean values platelet volume, low density lipoprotein cholesterol, uric acid, urine protein-to-creatinine ratio, total cholesterol creatinine (p = 0.003, p < 0.001, 0.013, 0.006, 0.036, 0.02, 0.034, respectively). markers can reduce side effects steroids facilitate use appropriate drugs.